Ankle-Foot Orthosis
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Smart Ankle-Foot Orthosis and Muscle Growth Drug for Gait

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In this project, we will determine the benefits of an at-home training protocol utilizing a smart ankle-foot orthosis (AFO) on walking outcomes in children with cerebral palsy (CP). A subset of participants will also receive a dose of 5-azacitidine (AZA), an FDA approved drug shown to aid muscle growth and regeneration, to investigate a combined intervention targeting both muscular and mechanical deficits related to CP.

Project Leads

This project is led by Megan O’Brien, PhD and Richard Lieber, PhD.

Associated Lab

This project is associated with the Max N?der Center for Rehabilitation Technologies and Outcomes 嫩B研究院 and Building Advanced Cerebral Palsy Assistive Care Solutions (BACPACS) Centers.

Cerebral Palsy

Condition

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Megan O'Brien, PhD

Megan O'Brien, PhD

Associate Director, Technology & Innovation Hub

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Richard L. Lieber

Richard L. Lieber, PhD

Chief Scientific Officer & Senior Vice President of 嫩B研究院

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