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This study investigates the effectiveness of daily acute intermittent hypoxia therapy (dAIH), coupled with a massed practice intervention or the use of high repetition training with the Rapael Glove, to improve upper-extremity function in individuals with chronic incomplete cervical SCI.

We seek to quantify the serum inflammatory markers in individuals with SCI, and correlate inflammation with responsiveness to AIH therapy.

The objective of this study is to measure the electrical activity of single muscle fibers and to determine how this electrical activity changes after botulinum toxin injections.

A team of scientists, led by researchers at Shirley Ryan ÄÛBÑо¿Ôº, Northwestern University and the University of Illinois at Chicago, has developed novel technology promising to increase understanding of how brains develop, and offer answers on repairing brains in the wake of neurotrauma and neurodegenerative diseases.

A new study published in the October 2022 issue of the Journal of NeuroEngineering and Rehabilitation from a research team led by SRAlab clinicians identified the cause of ¡ª and hope for a potential prevention of ¡ª nerve injuries in patients treated in the intensive care unit for severe COVID-19.

The Journal of Neurophysiology recently published a review by Adenike Adewuyi, MD PhD ¡ª a 2022 graduate of Shirley Ryan ÄÛBÑо¿Ôº¡¯s physical medicine and rehabilitation (PM&R) residency program ¡ª and her mentor, Colin Franz, MD, PhD, physician-scientist, at Shirley Ryan ÄÛBÑо¿Ôº. The review defines a clinical framework for evaluating patients with spinal cord injuries to determine their candidacy for nerve transfer surgery.

The overall objective of this study is to evaluate the impact of using the Nomad P-KAFO in people who have had a musculoskeletal or neurological injury that has affected their ability to walk.

This study is being done to conduct a preliminary investigation into a new prosthetic microprocessor controlled ankle, called the Damping, Stiffness, and Repositioning (DSR) ankle. Participants will visit the Shirley Ryan ÄÛBÑо¿Ôº 10-16 times over 9 weeks, each visit lasting approximately 3 hours, to perform a series of walking and mobility tests with both their own prosthetic ankle and the DSR ankle.

The goal of this double-blind, placebo-controlled, block-randomized clinical trial is to investigate the efficacy and potency of daily acute intermittent hypoxia (AIH) combined with transcutaneous electrical spinal stimulation (tSTIM) and skill-based walking practice.

The goal of the proposed study is to examine the neuromuscular mechanisms underlying the therapeutic effect of hippotherapy and determine whether repeated exposure to a pelvic perturbation force would be effective in improving trunk postural control and gait of children with cerebral palsy. This study is supported by NIH/NINDS, 1R01NS115487, Date of Project Period: 03/01/2020-02/28/2025

We aim to create new technology and techniques for studying physical and neurological trauma, using sensors, heaters, LED and arrays.

Every year, over 200,000 Americans sustain a peripheral nerve injury (PNI). Although peripheral nerves have the ability to spontaneously regenerate, 90% of PNI patients do not regain full motor function. Despite ongoing research, the main treatment for peripheral nerve injury¡ªsurgery¡ª continues to be performed without the assistance of any medication or other therapies to enhance the rate of axon regrowth.